丁香酚 Eugenol 丁子香酚 丁香油酚

CAS号 97-53-0
分子式 C10H12O2 分子量164.20
沸点 255°C
熔点 -12--10°C
折光率 1.54-1.542
敏感性 对空气和光线敏感
溶解性 Soluble in 100% ethanol, ether, oils, 70% alcohol, glacial acetic acid, chloroform, and aqueous sodium hydroxide. Insoluble in water.
存贮条件 储存温度2-8℃
密度 1.0700
应用 An antifungal antimicrobial agonist of the TRPV1 receptor.
产品介绍 具有强烈的丁香气和辛香气,在空气中色渐变深且稠。能与乙C、乙M、氯F和油类混溶，溶于冰乙酸和苛性J溶液，几乎不溶于水。低毒，半数致死量(大鼠，经口)2680mg/kg。有刺激性,是丁香的主要成分之一。
生化机理 Eugenol is a small molecule with structural analogy to Capsaicin that demonstrates agonism of the TRPV1 receptor. Eugenol is described to activate inward currents at the TRPV1, and this action is antagonized by the Capsaicin antagonist Capsazepine. Agonism of the TRPV1 by Eugenol has been correlated with an anesthetic effect. Eugenol also demonstrates antifungal and antimicrobial activity, showing efficacy against Candida albicans biofilms, Listeria monocytogenes and Escherichia coli. Eugenol is further described to induce reactive oxygen species (ROS) production and to scavenge ROS, thus demonstrating prooxidant and antioxidant effects.
别名 丁子香酚;丁香油酚;丁子香酸;4-烯丙基-2-甲氧基苯酚; 4-烯丙基愈创木酚;1-烯丙基-3-甲氧基-4-羟基苯;2-甲氧基-4-(2-丙烯基)苯酚;2-Methoxy-4-(2-propenyl)phenol; 4-Allyl-2-methoxyphenol; 4-Allylguaiacol