胶原酶V型/V型胶原酶/Collagenase Type V,≥1 FALGPA units/mg solid, >125 CDU/mg solid
- 产品编号：C0127
- 中文名称：胶原酶V型/V型胶原酶/Collagenase Type V
- 英文名称：Collagenase from Clostridium histolyticum
- 英文别名:Clostridiopeptidase A
- CAS号:9001-12-1
- 纯度:≥1 FALGPA units/mg solid, >125 CDU/mg solid
- EC号:232-582-9
- MDL号:MFCD00130830
订货信息：
产品规格价格(RMB)
- C0127-25MG 200
- C0127-100MG 450
- C0127-1G 2900
性能描述
| suitability | release of physiologically active rat pancreatic islets tested |
| storage temp. | ?20°C |
Application
Collagenase products offered by Sigma-Aldrich are prepared from culture supernatants of C. histolyticum. Most preparations contain collagenase, non-specifc protease, and clostripain activities. These enzymes act synergistically to degrade collagen and other intercellular material. Crude Collagenases are suitable for isolation of cells from many types of animal tissue. All are evaluated for their enzymatic activities. The optimal concentration for use and digestion time of tissue needs to be empirically determined. In addition, Sigma-Aldrich also offers collagenases which are tested for suitability for release of cells from specified tissues (release of rat pancreatic islets, rat epididymal adipocytes, and rat hepatocytes.
Collagenase from Clostridium histolyticum has been used in a study to investigate the degradation of collagen by the cariogenic bacteria, Streptococcus mutans. Collagenase from Clostridium histolyticum has also been used in a study to investigate the survivability of collagen micronetworks in the presence of collagenase.
