芦丁标准品/芸香甙/维生素P/紫皮甙芦丁/Rutoside/Rutin,≥99% (HPLC)
- 产品编号：R0105
- 中文名称：芦丁标准品/芸香甙/维生素P/紫皮甙芦丁/Rutoside/Rutin
- 英文名称：Rutin
- 英文别名:Quercetin-3-rutinoside hydrate, Vitamin P hydrate
- CAS号:153-18-4
- 分子式:C27H30O16
- 分子量:610.51
- 纯度:≥95% (HPLC)
- EC号:205-814-1
- MDL号:MFCD00149490
性能描述
| 试剂纯度 | ≥99% (HPLC) |
| form | powder |
| color | yellow to green |
| mp | 195 °C (dec.)(lit.) |
| 溶解性 | pyridine: soluble50 mg/mL |
| DMSO: soluble |
| aqueous base: soluble |
Biochem/physiol Actions
A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. Inclusion of rutin in the diet of rats significantly reduced the appearance of single-strand breaks in nuclear DNA caused by hepatocarcinogens aflatoxin B1 and N-nitrosodimethylamine. This protection from DNA damage was found to be due to a reduction in the induction of repair enzymes polymerase, DNA polymerase β and DNA ligase. Since DNA damage and inefficient repair are thought to initiate the process of carcinogenesis, effects of rutin on these functions suggests a protective role of this flavonoid against carcinogenesis induced by chemical carcinogens.
描述：浅黄色针状结晶（水），熔点 176-8°C, 23D +13.82°C（乙*），[]20D -39.43°C（吡*）。1g溶于7ml甲*、8000ml水、200ml沸水、23mL沸乙*、290mL冷乙*。UVλ CH3OH max nm:258.361。 IRνKBr max cm-1 :3400(OH), 1670(C=O), 1620、1520、1470(C6H5-) ，难溶于冷水，可溶于热水、甲*、乙*、吡*，易溶于碱水。
芦丁属维生素类药，有降低毛细血管通透性和脆性的作用，保持及恢复毛细血管的正常弹性。用作食品抗氧剂和色素。
