5-氨基乙酰丙酸盐酸盐/5-氨基乙酰丙酸
英文名称:5-Aminolevulinic acid hydrochloride
CAS号:5451-09-2
分子式:C5H9NO3·HCl
分子量:167.59
纯度:99%
EC号:226-679-5
MDL号:MFCD00012869
熔点 156-158°C
敏感性易吸潮;对光线敏感
溶解性 Soluble in dimethyl sulfoxide, methanol and water.
存贮条件储存温度2-8°C
密度 1.2310
溶解性:溶于水和乙醇。水中溶解度为50mg/ml,极微溶YM和乙酸乙酯。
应用 5-氨基乙酰丙酸盐酸盐可以用来激活或抑制HeLa和K562细胞系中血红素生物合成。它用于A431 ZL携带小鼠光动力ZL
生化机理 5-Aminolevulinic acid (5-ALA) is an intermediate in heme biosynthesis and being studied as an inducing reagent for protoporphyrin IX (PPIX) dependent fluorescence diagnosis of metastatic lymph nodes. 5-ALA is used for photodynamic therapy of diseases such as Paget’s disease and HPV infection-associated cervical condylomata acuminata.

