中文名称: 利巴韦林
英文名称: Ribavirin
别名: 三氮唑核苷;尼斯可 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
CAS.No: 36791-04-5 分子式: C8H12N4O5 分子量: 244.20
溶解性:
溶于DMSO(50mg/mL )和水(20mg/mL)
储存条件:
2-8℃
包装:
5g 25g 100g in poly bottle
产品描述:
一种广谱的抗病毒药,可抑制HCV,HIVl,RSV等病毒。
Ribavirin is an anti-viral drug used for severe RSV infection; hepatitis C infection, including if persistent, and often in combination with peginterferon alfa-2b or peginterferon alfa-2a; as well as some other viral infections. It is a guanosine (ribonucleic) analog used to stop viral RNA synthesis and viral mRNA capping, thus, it is a nucleoside inhibitor. Ribavirin is a prodrug, which when metabolized resembles purine RNA nucleotides. In this form it interferes with RNA metabolism required for viral replication. How it exactly affects viral replication is unknown; many mechanisms have been proposed for this but none of these has been proven to date. Multiple mechanisms may be responsible for its actions.

