| 性状: | 属性| 溶解性 | Soluble in DMSO (>10 mg/ml), water (25 mg/ml) Note: Phosphate-containing buffers may cause precipitation, and ethanol (<1 mg/mL) at 25 °C. |
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| 存贮条件 | 储存温度 2-8°C |
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| 熔点 | 260 °C |
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描述| 产品介绍 | Nafamostat Mesylate是一种抗凝血剂。 |
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| 用途 | A highly effective tryptase inhibitor. |
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| 生化机理 | Nafamostat mesylate is a highly effective tryptase (Ki=95.3 pM) inhibitor. The compound has the ability to promote synthesis of interferon-γ, tumor necrosis factor-α, IL-12, and IL-18. Additionally, Nafamostat mesylate can induce production of intercellular adhesion molecules-1, B7.1, B7.2, CD40 and CD40 ligand in human blood mononuclear cells. Nafamostat mesylate is an anticoagulant and has been shown to decrease levels of plasma myeloperoxidase, and has also been used in ERCP pancreatitis studies. Nafamostat mesylate is an inhibitor of Factor X, Factor XII, granzyme A and KLK. |
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| 包装 | N129262-10mg,N129262-50mg,N129262-250mg in glass bottle |
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